I've kept away from this because my views are known and I don't want to get into things with my Bonapeeps. 
I thought Oprah did well in parts, and failed miserably in others. Despite what was promised, there were clearly subjects that had been declared taboo in advance. He told the truth about his own use, he told half-truths about other things, avoided certain areas entirely, told some outright lies, showed more remorse for himself for getting caught, and for getting a "life sentence" than he did for his many victims, and ultimately admitted that he'd do or say just about anything to be able to take part in triathlons again!
He said that he looked up the word, "cheat" and decided it didn't apply to him because of the "level playing field". There was a tweet the next day that said he could better look of the word, "sociopath".
Meanwhile, ex Rabo riders are starting to 'come out' about the main Dutch team's doping practices going back to the 90's. The name of Dr. Leinders has fallen as he was a long time Rabo team doctor, who later worked for Sky. Leinders is now under investigation by the Belgian authorities. There is still so much more about the dirtiest era of cycling still to emerge.
Lance could help a lot if he would really come clean. However, telling the whole truth would seriously implicate others, and lay him open to US perjury charges. So, for the moment, until his immensely expensive team of legal advisers manage to arrange some kind of deal for him, Lance is still keeping his mouth shut.
He would have done better to keep it shut when he made that embarrassing, stupid, and downright disgraceful attempt at 'humor' by claiming he'd never called Betsy Andreu fat. I thought I saw Oprah shudder - would you make a 'fat' joke to Oprah? In case anyone missed her shocked and saddened reaction on Anderson Cooper just after the first interview, here it is.
http://www.youtube.com/watch?v=WTrkBRwT5Uc
btw, I love Betsy Andreu. 
RIP Iron Man
Rock On and keep the Faith
